Detection and transmission in chimpanzees of hepatitis B virus-related agents formerly designated "non-A, non-B" hepatitis.

Mutations at Nucleotide 1762, 1764 and 1766 of Hepatitis B Virus X Gene in Patients with Chronic Hepatitis B and Hepatitis B-Related Cirrhosis

Abstract       Background and objective: Hepatitis B virus (HBV) is a DNA virus with high tendency toward hepatic tissue. There are currently about 3 million HBV-infected people and 350 to 400 million chronic carriers of this virus in the world. X protein plays a role in the over-expression of oncogenes, carcinogenicity of liver cells and overlaps with the basal co...

Treatment of chronic hepatitis B, delta related liver disease and non-A non-B hepatitis.

Non-A, non-B hepatitis.

Diagnosis of non-A, non-B hepatitis (NANB) is made after exclusion of other known causes of hepatitis. Parenterally spread non-a, non-B hepatitis (PNANB) and enterally transmitted non-A, non-B hepatitis (ENANB) almost certainly appear to be two different diseases. The definite causative agents have not hitherto been identified. Much of our knowledge of NANB is based on (i) experimental studies ...

non-A, non-B hepatitis

1 Dodecanissou Street, Athens 12351, Greece. Abstract To assess the safety and possible efficacy of recombinant human interferon alfa-2b in preventing the development of chronic hepatitis, 24 adults (eight men, 16 women) with acute non-A, non-B (NANB) hepatitis were recruited to a pilot study. Half of the cases were parenterally transmitted and half were community acquired. Twelve patients rece...

Non A/non B hepatitis.

The concept that human viral hepatitis was caused by no more than two etiologic agents stemmed from early volunteer studies in which two epidemiologically distinct types of hepatitis were transmitted to humans (1). These experimentally transmitted diseases closely resembled two forms of naturally occurring viral hepatitis that could be distinguished on epidemiologic grounds. One form was highly...